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    Rockland:Epi-Plus系列抗体

    发布者:艾美捷科技    发布时间:2022-04-28     
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     组蛋白的甲基化、乙酰化和磷酸基化等翻译后修饰(PTM)是调节基因表达调控、DNA修复、染色体凝缩和精子形成的关键步骤。目前,已经确认许多蛋白能够形成复合物,起到调节组蛋白修饰的作用。 这些组蛋白修饰复合物的功能变化被认为破坏了组蛋白标记的结构和水平,从而解除了基于核染色质的过程控制,最终导致致癌转化和癌症的发展。与此一致的是,组蛋白PTM的异常模式与大量的人类恶性肿瘤有关。

     

    Rockland组蛋白PTM抗体.jpg

     

    众所周知,组蛋白的翻译后修饰(PTM)在表观遗传调控中发挥重要作用,研究组蛋白PTM过程中抗体是很重要的一环,组蛋白PTM的抗体是表观遗传学研究(如染色质免疫沉淀(ChIP)、免疫染色和免疫印迹)中的关键元素。然而,目前市面上许多组蛋白PTM抗体不能特异识别预定目标。今天小艾给大家带来知名品牌Rockland专利的组蛋白修饰相关抗体——Epi-Plus系列抗体,期望Epi-Plus凭借其无与伦比灵敏度和特异性给广大科研工作者组蛋白PTM研究带来新助力。

     

    Rockland Epi-Plus特点及优势:

    Rockland的高特异性Epi-Plus系列抗体可识别经过修饰的组蛋白和相关的细胞靶点,并通过多种检测方法进行验证。Epi-Plus抗体对这种修饰是特别灵敏和特异的,并且对相同位点或该蛋白其他氨基酸的其他修饰没有交叉反应。免疫荧光(IF)、免疫沉淀(IP)、染色质免疫沉淀(ChIP)、免疫组化(IHC)和蛋白印迹(WB)的分析验证了Epi-Plus抗体的有效性。

     

    Histone 3 K4 甲基化相关抗体:

    货号名称规格
    600-401-I57Anti-Histone H3 [Monomethyl Lys4] (RABBIT) Antibody50ug
    600-401-I58Anti-Histone H3 [Dimethyl Lys4] (RABBIT) Antibody50ug
    600-401-I59Anti-Histone H3 [Trimethyl Lys4] (RABBIT) Antibody50ug

     

    Epi-Plus?其他组蛋白修饰抗体推荐

    货号名称规格种属反应
    600-401-I52Histone H3 R2me1 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I53Histone H3 R2me2a Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I54Histone H3 K4me1/pT3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I55Histone H3 K4me2/pT3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I56Histone H3 pT3/K4ac Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I57Histone H3 K4me1 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I58Histone H3 K4me2 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I59Histone H3 K4me3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I60Histone H3 K4ac Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I61Histone H3 K4me1/pT6 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I62Histone H3 K4me3/pT6 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I63Histone H3 pT6 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I64Histone H3 K9me1/pT6 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I65Histone H3 K9me2/pT6 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I66Histone H3 K9me3/pT6 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I67Histone H3 R8me2a Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I68Histone H3 R8me2s Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I69Histone H3 K9me1 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I70Histone H3 K9me2 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I71Histone H3 K9me3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I72Histone H3 K9ac Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I73Histone H3 K9ac/K14ac Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I74Histone H3 pS10 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I75Histone H3 pS10/pT11 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I76Histone H3 pT11 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I77Histone H3 R17me2a Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I78Histone H3 K18me1 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I79Histone H3 K18me2 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I80Histone H3 K18me3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I81Histone H3 K18ac Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I82Histone H3 K23ac Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I83Histone H3 pS28 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I84Histone H3 K27me3/pS28 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I85Histone H3 R2me2s/K4me2 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I86Histone H3 K36me1 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I87Histone H3 K36me2 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I88Histone H3 K36me3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I89Histone H3 K36ac Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I90Histone H3 K37me1 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I91Histone H3 K37me2 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I92Histone H3 K37me3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I93Histone H3 K56me1 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I94Histone H3 K56me3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-I95Histone H3 K79Me3 Antibody50ugHuman, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
    600-401-J98Histone H3 K4-Me3/K9-Ac Antibody50ugHuman, mouse, rat, C. elegans
    600-401-J99Histone H3 K27me3 Antibody50ugHuman, mouse, rat, C. elegans
    600-401-K00Histone H3 K27ac Antibody50ugHuman, mouse, rat, C. elegans
    600-401-K01Histone H3 K4me2/pT6 Antibody50ugHuman, mouse, rat, C. elegans
    600-401-K02Histone H3 K23me2 Antibody50ugHuman, mouse, rat, C. elegans
    600-401-M75Histone H3 K27 methyl Antibody50ugHuman, mouse, rat, C. elegans
    600-401-P08Histone H3 K9-Ac/pS10 (RABBIT) Antibody50ugHuman
    600-401-P10Histone H3 K79-Me1 Antibody50ugHuman, Mouse, Primate, C. elegans, Drosophila, Plant, Rat, Xenopus
    600-401-P14Histone H3 pT3/R2-Me2s Antibody50ugHuman
    600-401-V34Histone H3 K27 me2 Antibody50ugHuman
    600-401-W54Histone H3 K27 me1 Antibody50ugHuman

    *以上产品仅供科研使用,不得用于医疗及诊断.

     

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